ORIGINAL PAPER
Sociodemographic and medical correlates of fertility-related quality of life in primary infertile Czech couples attending fertility clinics
1
Reprofit International Ostrava, Moravská Ostrava a Přívoz, Czech Republic
2
Faculty of Medicine and Dentistry, Palacký University Olomouc, Olomouc, Czech Republic
3
Department of Chemical Education and Humanities, University of Chemistry and Technology, Prague, Czech Republic
4
Reprofit International Brno, Brno-Střed, Czech Republic
5
Center for Sexual Health and Interventions, National Institute of Mental Health, Klecany, Czech Republic
These authors had equal contribution to this work
Submission date: 2025-04-14
Final revision date: 2025-09-21
Acceptance date: 2025-11-05
Online publication date: 2026-01-27
Publication date: 2026-01-28
Corresponding author
Lenka Martinec Nováková
Department of Chemical Education and Humanities, University of Chemistry and Technology, Prague, Technická 5, 166 28 Prague 6 – Dejvice, Czech Republic
Department of Chemical Education and Humanities, University of Chemistry and Technology, Prague, Technická 5, 166 28 Prague 6 – Dejvice, Czech Republic
Health Psychology Report 2026;14(1):39-70
KEYWORDS
TOPICS
ABSTRACT
Background:
Infertility significantly impacts couples’ quality of life (QoL), with women often reporting a greater psychological burden. However, evidence regarding the effects of socioeconomic and medical variables remains mixed, particularly for couples with primary infertility in Central/Eastern Europe. This study used a dyadic approach to investigate how gender, medical history, and sociodemographic factors affect fertility-related QoL (FertiQoL) in Czech couples seeking treatment for primary infertility.
Participants and procedure:
This cross-sectional multicenter study included 469 heterosexual couples diagnosed with primary infertility from four Czech fertility clinics. Participants completed the FertiQoL questionnaire and a sociodemographic survey. Medical data were provided by attending physicians. The Actor-Partner Interdependence Model (APIM) was employed to analyze the interdependent data from the couples.
Results:
A significant gender effect was found, with women reporting lower total, Emotional, Mind-Body, and Social FertiQoL scores than their male partners. The cause of infertility was a key moderator: men with a male-factor or mixed-factor diagnosis reported lower Emotional and Mind-Body QoL, whereas women’s scores were consistently low regardless of etiology. Prior experience with assisted reproductive technology (ART) was associated with lower Emotional scores for both partners, while lower Mind-Body scores were observed for women only. Residing in mid-sized cities and having a higher household income were associated with better QoL. Conversely, longer relationship duration was negatively associated with total, Relational, and Social scores.
Conclusions:
The findings underscore the necessity of integrating psychological support into standard fertility care. A dyadic, context-sensitive approach is crucial for identifying and supporting at-risk groups. Interventions should be proactively offered to all patients, with a targeted focus on women – especially those with prior ART experience – and men diagnosed with male-factor infertility, who represent a distinct vulnerable population requiring tailored support.
Infertility significantly impacts couples’ quality of life (QoL), with women often reporting a greater psychological burden. However, evidence regarding the effects of socioeconomic and medical variables remains mixed, particularly for couples with primary infertility in Central/Eastern Europe. This study used a dyadic approach to investigate how gender, medical history, and sociodemographic factors affect fertility-related QoL (FertiQoL) in Czech couples seeking treatment for primary infertility.
Participants and procedure:
This cross-sectional multicenter study included 469 heterosexual couples diagnosed with primary infertility from four Czech fertility clinics. Participants completed the FertiQoL questionnaire and a sociodemographic survey. Medical data were provided by attending physicians. The Actor-Partner Interdependence Model (APIM) was employed to analyze the interdependent data from the couples.
Results:
A significant gender effect was found, with women reporting lower total, Emotional, Mind-Body, and Social FertiQoL scores than their male partners. The cause of infertility was a key moderator: men with a male-factor or mixed-factor diagnosis reported lower Emotional and Mind-Body QoL, whereas women’s scores were consistently low regardless of etiology. Prior experience with assisted reproductive technology (ART) was associated with lower Emotional scores for both partners, while lower Mind-Body scores were observed for women only. Residing in mid-sized cities and having a higher household income were associated with better QoL. Conversely, longer relationship duration was negatively associated with total, Relational, and Social scores.
Conclusions:
The findings underscore the necessity of integrating psychological support into standard fertility care. A dyadic, context-sensitive approach is crucial for identifying and supporting at-risk groups. Interventions should be proactively offered to all patients, with a targeted focus on women – especially those with prior ART experience – and men diagnosed with male-factor infertility, who represent a distinct vulnerable population requiring tailored support.
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